Which of the following is the best estimate of the effect of the Portfolio Diet on the reduction of low-density-lipoprotein (LDL) levels?

The Portfolio Diet has been specifically designed to improve cardiovascular health by targeting the reduction of low-density lipoprotein (LDL) cholesterol levels. This diet focuses on combining various plant-based foods that are rich in healthy fats, fiber, and specific nutrients, which have been shown to effectively lower cholesterol levels.

Research indicates that adherence to the Portfolio Diet can lead to significant reductions in LDL cholesterol. Studies have reported that individuals following this diet can experience an average reduction in LDL levels of approximately 28%. This substantial decrease is primarily due to the inclusion of specific food components such as plant sterols, nuts, soy protein, and soluble fiber, which work together synergistically to inhibit cholesterol absorption and promote its elimination from the body.

This level of LDL reduction aligns with clinical findings and dietary guidelines suggesting that significant dietary changes can lead to notable improvements in cholesterol management. Therefore, the estimate of 28% is the best reflection of the impact this diet can have on lowering LDL cholesterol levels.