What is the primary health risk associated with prolonged sitting?

The primary health risk associated with prolonged sitting is increased cardiovascular disease. Extended periods of sitting have been linked to various adverse health effects, particularly cardiovascular issues. When individuals sit for long durations, there is a decrease in the metabolic rate, which can lead to adverse changes in body composition, including increased body fat and decreased levels of HDL (high-density lipoprotein) cholesterol. These factors contribute significantly to the development of cardiovascular disease, as they can elevate blood pressure, inflammation, and insulin resistance.

Moreover, studies have shown that prolonged sitting is associated with higher mortality rates from cardiovascular diseases. Regular movement and physical activity are essential to help mitigate these effects and promote heart health. While decreased muscle mass and reduced flexibility are also consequences of excessive sedentary behavior, they are not as closely linked to immediate health risks as cardiovascular issues.