What is the lifetime risk for women with 2 or more risk factors for cardiovascular disease according to the Framingham heart study?

The lifetime risk for women with two or more risk factors for cardiovascular disease is indeed around 50% according to the Framingham Heart Study. This study established a framework for understanding the risk factors associated with cardiovascular disease and emphasized that having multiple risk factors significantly increases the probability of developing heart disease over a person's lifetime.

For women, two or more risk factors—such as hypertension, hyperlipidemia, diabetes, smoking, or a family history of heart disease—interact in ways that collectively elevate their risk. Statistically, this means that nearly half of women with these contributing factors will experience cardiovascular events, underscoring the importance of risk assessment and management in this population.

Other percentages like 20%, 30%, or 8% do not accurately reflect the significant risk associated with having multiple risk factors, as highlighted by extensive research following the Framingham cohort. This understanding guides preventive strategies and lifestyle changes in clinical practice to mitigate these risks.